You significantly increase your chances of a positive result when you take time to craft a tailored response to a specific meeting planner. Just like any job application, you want to select opportunities where you feel you're an ideal fit. It's up to you to communicate to the meeting planner just how you're a great fit. That often means pleasantly persistent follow-up.
Meeting planners are evaluating multiple candidates. The one who shines the most is going to get the job. If it seems like you're just using a standard form letter response and not doing any meaningful followup, you will most likely drop off a meeting planner's radar.
We have a tool for speakers to save application templates to make life a little easier. Use templates to fill in the standard material, but be sure to customize your messaging for each meeting planner before hitting the "submit" button.